Severe Acute Respiratory Syndrome Coronavirus 2 and the Digestive System

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Paolo Sossai, Silvia Uguccioni, Francesco Amenta




SARS-CoV-2, COVID-19, Coronavirus, Digestive diseases,

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Perlman S, McIntosh K, 2020, Coronaviruses, including severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. Elsevier, Philadelphia, PA. DOI: 10.1016/b978-1-4557-4801- 3.00157-0.

Available from: [Last accessed on 2020 Dec 26].

Zhou P, Yang XL, Wang XG, et al., 2020, A Pneumonia Outbreak Associated with a New Coronavirus of Probable Bat Origin. Nature, 579:270–273.

Yao H, Lu X, Chen Q, et al., 2020, Patient-Derived Mutations Impact Pathogenicity of SARS-CoV-2, medRxiv. DOI: 10.1101/2020.04.14.20060160.

Shi X, Gong E, Gao D, et al., 2005, Severe Acute Respiratory Syndrome Associated Coronavirus is Detected in Intestinal Tissue of Fatal Cases. Am J Gastroenterol, 100:169–76.

Zhang H, Penninger JM, Li Y, et al., 2020. Angiotensin-converting Enzyme 2 (ACE2) as a SARS-CoV-2 Receptor: Molecular Mechanism and Potential Therapeutic Target. Intensive Care Med, 46:586–90. DOI: 10.1007/s00134- 020-05985-9.

Li MY, Li L, Zhang Y, et al., 2020, Expression of the SARS-CoV-2 Cell Receptor Gene ACE2 in a Wide Variety of Human Tissues. Infect Dis Poverty, 28(9):45. DOI: 10.1186/s40249-020-00662-x.

Minodier L, Masse S, Capai L, et al., 2017, Clinical and Virological Factors Associated with Gastrointestinal Symptoms in Patients with Acute Respiratory Infection: A Two-year Prospective Study in General Practice Medicine. BMC Infect Dis, 17:729. DOI: 10.1186/s12879- 017-2823-9.

Huang C, Wang Y, Li X, et al., 2020, Clinical Features of Patients Infected with 2019 Novel Coronavirus in Wuhan, China. Lancet, 395:497–506.

Wang D, Hu B, Hu C, et al., 2020, Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus-infected Pneumonia in Wuhan, China. JAMA, 323:1061–9. DOI: 10.1001/jama.2020.1585.

Zhou Z, Zhao N, Shu Y, et al., 2020, Effect of Gastrointestinal Symptoms on Patients Infected with COVID-19. Gastroenterology, 158:2294–7. DOI: 10.1053/j. gastro.2020.03.020.

Holshue ML, DeBolt C, Lindquist S, et al., 2020, First Case of 2019 Novel Coronavirus in the United States. N Engl J Med, 382:929–36.

Cheung KS, Hung IF, Chan PP, et al., 2020, Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples from a Hong Kong Cohort: Systematic Review and Meta-analysis. Gastroenterology, 159:81–95. DOI: 10.1053/j.gastro.2020.03.065.

Sun J, Aghemo A, Forner A, et al., 2020, COVID-19 and Liver Disease. Liver Int, 40:1278–81. DOI: 10.1111/ liv.14470.

Fix OK, Hameed B, Fontana RJ, et al., 2020, Clinical Best Practice for Hepatology Transplant Providers During the COVID-19 Pandemic: AASLD Expert Panel Consensus Statement. Hepatology, 72:287–304. DOI: 10.1002/ hep.31281.

Rubin DT, Feuerstein JD, Wang AY, et al., 2020, AGA Clinical Practice Update on Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: Expert Commentary. Gastroenterology, 159:350–7. DOI: 10.1053/j.gastro.2020.04.012.

Lui RN, Wong SH, Sánchez-Luna SA, et al., 2020, Overview of Guidance for Endoscopic During the Coronavirus Disease 2019 (COVID-19) Pandemic. J Gastroenterol Hepatol, 35:749–59.

Chai N, Mei Z, Zhang W, et al., 2020, Endoscopy Works During the Pandemic of Coronavirus COVID-19: Recommendations by the Chinese Society of Digestive Endoscopy. United Eur Gastroenterol J, 8:798–803. DOI: 10.1177/2050640620930632.

Ai T, Yang Z, Hou H, et al., 2020, Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology, 296:E32–40. DOI: 10.1148/radiol.2020200642.

Parvez MK, 2020, Gastrointestinal and Hepatobiliary Manifestations of Coronavirus Disease-19: Potential Implications for Healthcare Resource-deficient Countries. Gastroenterol Hepatol Lett, 2:7–11.

Sossai P, Uguccioni S, Mela GS, et al., 2020, Coronavirus Variant COVID-19 Pandemic: A Report to Seafarers. Int Marit Health, 71:191–4. DOI: 10.5603/imh.2020.0034.



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