A Review on the Clinicopathological Features and Management of the Celiac Disease

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Fenglan Wang, Yonglin Liu, Shuying Lou, Xiaoqin Li, Linna Wang, Fuyong Jiao, Md Rezaul Karim, Abu Taiub Mohammed Mohiuddin Chowdhury


Celiac disease (CD) is a multifactorial and chronic autoimmune disease caused by the ingestion of gluten. Epidemiological studies have shown that the disease is currently becoming more common worldwide. Among the countries, North America, North Europe, and Australia have high prevalence of CD. CD is often confused with other chronic gastrointestinal tract-related diseases. Therefore, it is important to have a broad understanding of the clinicopathological features of CD. This review aims to illustrate the epidemiology, pathogenesis, clinical manifestation, and diagnosis and treatment of CD.


Celiac disease, Gluten, Tissue transglutaminase, Small intestine biopsies

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DOI: http://dx.doi.org/10.18063/ghl.v2i2.257


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